Zone Formation and Resolution

Most electrophoretic methods have been tried in a free-flow format, including isoelectric focusing, native zone electrophoresis, and isotachophoresis. Most free-flow electrophoresis equipment has very low (ca 1 g/(L-h)) capacity, and resolution is reduced by heating and electroosmotic considerations. 

In terms of organization, the text has two main parts. The first six chapters constitute generic background material applicable to a wide range of separation methods. This part includes the theoretical foundations of separations, which are rooted in transport, flow, and equilibrium phenomena. It incorporates concepts that are broadly relevant to separations diffusion, capillary and packed bed flow, viscous phenomena, Gaussian zone formation, random walk processes, criteria of band broadening and resolution, steady-state zones, the statistics of overlapping peaks, two-dimensional separations, and so on. 

The bifurcation mechanisms for formation of multi-slip fault zones suggest that maximum fault zone thickness will often correspond to the strike-normal distance between the traces of two overlapping slip surfaces (Fig. 2c). Fault overlaps and their breached equivalents occur on faults of all sizes as do, by implication, paired and multi-slip surface fault zones. Complex and paired slip surface fault zone structures will occur on scales below that resolvable by even high quality seismic data (lateral resolution is no better than 50-100 m at North Sea reservoir depths). The possible impact of sub-seismic complexity and paired slip surfaces on connectivity and sealing across faults offsetting an Upper Brent type sequence are briefly considered below. 

Giddings (1990) presented a derivation applicable to both the planar format such as TLC that is distance-based and the comprehensive multidimensional separations that are time-based. The resolution was shown to be equal to the Euclidean norm of zone resolution components. This can be summarized as... 

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