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Zanamivir structure-based design

FIGURE 30.2 The first marketed drugs derived from structure-based design, (a) captopril (Capoten ), (b) dorzolamide (Trusopt ), (c) zanamivir (Relenza ), and (d) oseltamivir (Tamiflu ). [Pg.608]

Figure 7.16 Dihydrofolate reductase inhibitors methotrexate and Compound 7, (El-Hamamsy, M.H.R.L et al. Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis. Bioorg. Med. Chem. 2007, 15, 4552-4576.), neuraminidase inhibitor Relenza (zanamivir), and CCR5 blocker apiaviroc. Figure 7.16 Dihydrofolate reductase inhibitors methotrexate and Compound 7, (El-Hamamsy, M.H.R.L et al. Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis. Bioorg. Med. Chem. 2007, 15, 4552-4576.), neuraminidase inhibitor Relenza (zanamivir), and CCR5 blocker apiaviroc.
Structure-Based Sialidase Inhibitor Design on a Sialic Acid Scaffold Development of Zanamivir... [Pg.464]

See other pages where Zanamivir structure-based design is mentioned: [Pg.144]    [Pg.381]    [Pg.335]    [Pg.274]    [Pg.144]    [Pg.609]    [Pg.12]    [Pg.97]    [Pg.861]    [Pg.609]    [Pg.852]    [Pg.139]    [Pg.132]    [Pg.133]    [Pg.323]    [Pg.341]    [Pg.251]    [Pg.646]    [Pg.736]    [Pg.740]   
See also in sourсe #XX -- [ Pg.451 ]

See also in sourсe #XX -- [ Pg.451 ]



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Design Bases

Design structures

Structure based design

Structure designable

Structure-Based Sialidase Inhibitor Design on a Sialic Acid Scaffold Development of Zanamivir

Zanamivir

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