Xestospongia exigua

Further members of this class of alkaloids are the araguspongines K (10) and L (11), isolated from the marine sponge Xestospongia exigua collected at Bayadha, on the Saudi Arabian Red Sea coast [16]. After evaporation of the EtOH extract, it was partitioned between hexanes and MeCN. The polar fraction was subjected to a series of chromatographic separations by column chromatography on silica gel. The structures of both alkaloids 10 and... 

Motuporamines A (52), B (S3), and C (54), which contain a spermidine-like substmcture, represent a new family of cytotoxic sponge alkaloids, were isolated as an inseparable mixture from Xestospongia exigua collected in Papua New Guinea [29]. 

Motuporamines A-I 49-55 were found in the extract from the marine sponge Xestospongia exigua Kirkpatrick collected off Motupore Island, Papua New Guinea [48,49]. The structures of the motuporamines are composed of a 13-, 14-, or... 

Orabi and coworkers [114] reported the elucidation ofthe structures of several bis-1 -oxaquinolizidine N-oxide alkaloids from Red Sea specimens of Xestospongia exigua, employing long-range HMBC data in the process. Two of the compounds... 

Structures of Xestospongin A, B, C and D, Novel Vasodilative Compounds from Marine Sponge Xestospongia exigua. Nakagawa, M. Endo, M. Tanaka, N. and Gen-Pei, L. Tetrahedron Lett. 1984,25, 3227. 

Xastospongins. Epimeric alkaloids (X. A-D) from the marine sponge Xestospongia exigua, related to petrosin, e.g. X. A (araguspongin D) CzgHjoNjOj, Mr 446.72, cryst., mp. 135-136 °C, [ajp+7° (CHCI,). X. show vasodilatory and antimicrobial activity and bind to the IPj-receptor. ... 

Xestospongia exigua Nakagawa et al., 1984 Hoye, North, and Yao, 1994 Baldwin et al, 1998b... 

Williams, D.E., Lassota, P., and Andersen, R.J. (1998) Motuporamines A-C, cytotoxic alkaloids isolated from the marine sponge Xestospongia exigua (Kirkpatrick)./. Org. Chem., 63, 4838—4841. 

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