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Xantine oxidase

Bray, M. R., and R. J. Deeth. 1996. A density functional study of active site models of xantine oxidase. Inorganic Chemistry 35, 5720. [Pg.125]

There are many metabolic reactions that may generate 0 2. The most common is the transformation of arachidonic acid into a prostaglandin, or the production of norepinephrine from dopamine. In the cascade of production of uric acid from xantine, ROS are generated from hypoxantine to xantine and in the following step from xantine to uric acid, H202 and 0 2 are formed respectively, through the same enzyme—xantine oxidase. [Pg.214]

As a class, PPs are considered active as antioxidant, antithrombogenic, and anti-inflammatory compounds. Many of them show an in vitro activity as scavengers of a wide range of RS, and also show inhibition of cycloxygenase and lipoxygenase (59,60), xantine oxidase (61), metalloproteases (62), and angiotensin II converting enzyme (63). All these activities are... [Pg.226]

Van Hoorn DEC, Nijveldt RJ, Van Leewen PAM, et al. Accurate prediction of xantine oxidase inhibition based on the structure of flavonoids, EurJ Pharmacol 2002 541 1 I I-I 18. [Pg.234]

Figure 3. Effect of MWCNT on a) amount of hydroxyl radicals generated by photolysis of hydrogen peroxide, measured by ESR/spin trapping technique b) amount of superoxide radicals generated by a xantine/xantine oxidase system, measured by UV spectroscopy. Light gray bars no NT, dark gray bars in the presence of NT.31... Figure 3. Effect of MWCNT on a) amount of hydroxyl radicals generated by photolysis of hydrogen peroxide, measured by ESR/spin trapping technique b) amount of superoxide radicals generated by a xantine/xantine oxidase system, measured by UV spectroscopy. Light gray bars no NT, dark gray bars in the presence of NT.31...
Pan, S., Andrews, P.A., Glover, C.J., and Bachur, N.R., 1984, Reductive activation of mitomycin C and mitomycin C metabolites catalysed by NADPH-cytochorome P-450 reductase and xantine oxidase. J. Biol. Chem. 259 959-962 Pollakis, G., Goormaghtigh, E., and Ruysschaert, J.-M., 1983, Role of quinone structure in the mitochondrial damage induced by antitumor anthracyclines. FEBS Lett. 155 267-272 Rappaport, S.M., McDonald, T.A., and Yeowell-O Connell, K., 1996, The use ofprotein adducts to investigate the disposition of reactive metabolites of benzene. Environ. Health Perspect. 104Suppl6 1235-1237... [Pg.168]

MA-St 4-amino-6-hydroxypyrazolo[3,4-d]pyrimidine (inhibitor of xantin oxidase, anti-hypertensive) 133... [Pg.289]

Cofactor of enzymes xantine and aldehyde oxidase copper antagonist... [Pg.59]


See other pages where Xantine oxidase is mentioned: [Pg.168]    [Pg.294]    [Pg.227]    [Pg.309]    [Pg.442]    [Pg.168]    [Pg.294]    [Pg.227]    [Pg.309]    [Pg.442]    [Pg.156]    [Pg.269]   
See also in sourсe #XX -- [ Pg.95 ]

See also in sourсe #XX -- [ Pg.8 , Pg.10 ]




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Xantine

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