Worm-like fibrils

Fig. 15.5. Schematic models of supramolecular fibrillar assemblies of Afi(l-40) fibrils. Variation in morphology can arise at the level of oligomeric species, protofilaments, or initial short fibrils. They associate together on the quartz surface, creating three types of supramolecular fibrillar assemblies Straight fibrils (Type I), spherulitic assemblies (Type II), and worm-like fibrils (Type III). A mixed architecture of type I and fibrils (Type I/II) was also observed when the internal density is coarse. It is to be noted that the different precursors are represented together in a box and that the relationships between amyloid precursors and final products remain unclear. Reproduced from [18] with permission...

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