Wittig Reactions Investigated in Micro Reactors

Organic synthesis 78 [OS 78] 2-Nitrobenzyltriphenylphosphonium bromide and four aldehydes 

The testing of 2-nitrobenzyltriphenylphosphonium bromide and methyl 4-formylbenzoate and four other aldehydes, 3-benzyloxybenzaldehyde, 2-naphthaldehyde, 5-nitrothiophene-2-carboxaldehyde and 4-[3-dimethylamino)propoxy]benzaldehyde, has been reported [13]. 

Oiganic synthesis 79 [OS 79] Methyl diethoxyphosphonoacetate and 4-methoxybenzaldehyde (Wittig-Horner-Emmons) 

4-Methoxybenzaldehyde and methyl diethoxyphosphonoacetate were reacted via the Wittig-Horner-Emmons route to give the corresponding alkene product [85] (see a more detailed description in [42]). 

Conversion/selectivity/yield - benchmarking to batch synthesis 

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