Winthrop Chemical

Eisleb, O. US Patent 2,167,351 July 25, 1939 assigned to Winthrop Chemical Company, Inc. 

Reitmann, J. Ahphatic amine salts of halogenated pyridones containing an add group. US Patent 1,993,039 (March 5, 1935, to Winthrop Chemical Company Inc., New York), 1935. 

Bockmiihl, M., Krohs, W., Racke, E., Windisch, K. N-methylsul-phites and V-methanesulphinic add salts of l-aryl-2,3-dialkyl-4-alkylaminopyrazolones. US Patent 2,193,788 (March 19, 1940 Winthrop Chemical Company, Inc.), 1940. 

After Allied troops had captured Tunis in May of 1943, the drug fell together with pharmacological reports into the hands of Americans, who confirmed back home its superior efficacy compared to quinine and atabrine. The latter, an acridine dye, also known as mepacrine, originated as well from the discovery programme at Bayer and was first synthesised by Fritz Mietzsch and Hans Mauss and tested by Walter Kikuth around 1932. Bayer s collaboration and distribution partner in the US, Winthrop Chemical Corporation, had increased its production of atabrine by 1944 to annually 3,500 million tablets, with an additional 2 million tablets from the British ICl, in support of Allied forces. The... 

In 1926, the Bayer 50 % interest in the profits of Winthrop Chemical would be transformed into a 50% equity ownership in Winthrop Chemical. Wilkins, "History" (ref. 2). 

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