What Is the Most Common Reaction Theme of Aldehydes and Ketones

4 What Is the Most Common Reaction Theme of Aldehydes and Ketones  

The partially positive charge on the carbonyl carbon (Section 12.3) is the cause of the most common reaction theme of the carbonyl group, the addition of a nucleophile to form a tetrahedral carbonyl addition intermediate. In the following general reaction, the nucleophilic reagent is written as Nu to emphasize the presence of its unshared pair of electrons  

5 What Are Grignard Reagents, and How Do They React with Aldehydes and Ketones  

From the perspective of the organic chemist, the addition of carbon nucleophiles is the most important type of nucleophilic addition to a carbonyl group because these reactions form new carbon-carbon bonds. In this section, we describe the preparation and reactions of Grignard reagents and their reaction with aldehydes and ketones. 

Carbanion An anion in which carbon has an unshared pair of electrons and bears a negative charge. 

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