Weinstock variant of the Curtius rearrangement

The Weinstock variant of the Curtius rearrangement has also foimd application in amino acid synthesis. For example, a route toward y amino acids employed a chiral auxiliary to prepare alkylated succinic acid monoester 64 in enantiomerically enriched form. Under the Weinstock conditions, smooth rearrangement to the isocyanate occurred, and, without isolation, this was heated with tert-butyl alcohol, providing the Boc-protected y5-amino ester 65. ... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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