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Watson-Hoogsteen groove

Figure 11.6. A TAT triplet showing the positioning of the three grooves and the neomycin binds to the larger triplex Watson-Hoogsteen (W-H) groove. Figure 11.6. A TAT triplet showing the positioning of the three grooves and the neomycin binds to the larger triplex Watson-Hoogsteen (W-H) groove.
Figure 11 Triple-helix grooves (a) the Watson-Crick (strands I and II) minor groove of the duplex (b) the Crick-Hoogsteen (strands II and III) groove and (c) the Watson-Hoogsteen (strands I and III) groove. The grooves in (b) and (c) are formed by partition of the major groove of the DNA duplex by a Hoogsteen strand... Figure 11 Triple-helix grooves (a) the Watson-Crick (strands I and II) minor groove of the duplex (b) the Crick-Hoogsteen (strands II and III) groove and (c) the Watson-Hoogsteen (strands I and III) groove. The grooves in (b) and (c) are formed by partition of the major groove of the DNA duplex by a Hoogsteen strand...
Arya dp, Micovic L, Charles I, CoEEEE RL, Willis B, Xue L, Neomycin binding to Watson-Hoogsteen (W-H) DNA triplex groove a model, J. Am. Chem. Soc. 2003 125 3733-3744. [Pg.225]


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See also in sourсe #XX -- [ Pg.273 ]




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Grooves

Grooving

Hoogsteen

Watson

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