Water-insoluble chrome compounds

The level of concern for health hazards frequently depends on the chemical form of the metal compounds. This is primarily because the critical influence of chemical form on the uptake of inhaled, ingested, or skin-deposited materials, and can result in substantially different exposure limits for different compounds. For example, the ACGIH TWA TLV for exposure to chromium compounds is most restrictive for insoluble hexavalent chromium compounds (0.01 mg/m ), which are poorly removed from lung following inhalation less restrictive for water-soluble hexavalent compounds (0.05 mg/m ), which are more readily absorbed into the bloodstream following inhalation and least restrictive for the less-reactive trivalent chromium compounds and chromium metal (0.5 mg/m ) (11). Chromic acid and chromate aerosols can be caustic to mucous membranes, and some water-insoluble chrome IV compounds are carcinogens. In addition,... 

Lead chromate, a water-insoluble compound also called Chrome Yellow and used as a pigment, is an A2 suspected human lung carcinogen and can cause chronic lead poisoning (lARC [19]). 

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