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Viscum viscotoxins

Viscum viscotoxin Viscum album (misdetoe) Apoptotic (DNA... [Pg.394]

Viscum Viscotoxins A1, A2, Viscum album (mistletoe) — leakage aggregation antifungal] PM [permeabilize PM ... [Pg.516]

Figure 3 Comparison of several thionins reveals their structural similarity. The structures are color coded for their secondary structure, cyan a-helix, red /3-strand, magenta random coil/turn. (a) a-Purothionin (2plh) and (b) /3-purothionin (1 bhp) have four disulfide bonds, (c) Crambin (1 ejg) has three disulfide bonds. Despite its thionin fold it lacks antimicrobial or other toxic activity, (d) An overlay of crambin (1ejg, black), a-purothionin (2plh, red), /3-purothionin (1 bhp, orange), viscotoxin A3 (ledO, magenta), and viscotoxin B (Ijmp, cyan) from Viscum album reveals the conserved structure of the peptide backbone. Figure 3 Comparison of several thionins reveals their structural similarity. The structures are color coded for their secondary structure, cyan a-helix, red /3-strand, magenta random coil/turn. (a) a-Purothionin (2plh) and (b) /3-purothionin (1 bhp) have four disulfide bonds, (c) Crambin (1 ejg) has three disulfide bonds. Despite its thionin fold it lacks antimicrobial or other toxic activity, (d) An overlay of crambin (1ejg, black), a-purothionin (2plh, red), /3-purothionin (1 bhp, orange), viscotoxin A3 (ledO, magenta), and viscotoxin B (Ijmp, cyan) from Viscum album reveals the conserved structure of the peptide backbone.
Figure 6 Three-dimensional structure of viscotoxin B (1JMP) from mistletoe (Viscum album). Figure 6 Three-dimensional structure of viscotoxin B (1JMP) from mistletoe (Viscum album).
The stems and leaves of Viscum album (all heal, bird hme, devil s fuge, golden bough, mistletoe) contain alkaloids, viscotoxins, and lectins. While the toxicity of... [Pg.3641]

Viscum contain lectins that are cytotoxic by inhibiting protein synthesis on the ribosomal level in a manner similar to the toxalbumins ricin and abrin. Viscotoxin and phoratoxin are cardiac toxins and vasoconstrictors. Both produced reflex bradycardia, negative inotropic effects, and, in high doses, vasoconstriction of skin and skeletal muscle vessels in animals. [Pg.1701]

Olson, T, Samuelsson, G. Purification of viscotoxin Aox2 from the European Mistletoe (Viscum album L.) by chromatography on DEAE-cellulose. Acta Chem. Scand. 1970, 24, 720-721... [Pg.497]

Bauer, C., T. Oppel, F. Rueff, and B. Przybilla. 2005. Anaphylaxis to viscotoxins of mistletoe (Viscum album) extracts. Ann. Allergy Asthma Immunol. 94(l) 86-89. [Pg.930]

Olson, J. and G. Samuelsson, The amino acid sequence of viscotoxin A2 from the European mistletoe (Viscum album), Acta Chem. Scand, 2<5, 585-595 (1972). [Pg.246]

Konopa, J., Woynarowski, J. M., and Lewandowska-Gunieniak, M., 1980, Isolation of viscotoxins cytotoxic basic polypeptides from viscum album L., Hoppe Seyler sZ. Physiol Chem., 131 1525. [Pg.290]


See other pages where Viscum viscotoxins is mentioned: [Pg.98]    [Pg.122]    [Pg.244]    [Pg.156]    [Pg.9]    [Pg.86]   
See also in sourсe #XX -- [ Pg.4 , Pg.4 , Pg.4 , Pg.7 , Pg.9 , Pg.12 ]




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