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Virtual screening novel lead identification

Successful Identification of Novel Leads through Virtual Screening... [Pg.72]

X-ray analysis of a ligand complex led to the discovery of a new, unexpected binding mode 150 involving a main-chain peptide flip, and a water molecule. This observation was then exploited to define a new pharmacophore for virtual screening, leading to the identification of novel sub-micromolar inhibitors. [Pg.625]

See other pages where Virtual screening novel lead identification is mentioned: [Pg.38] [Pg.510] [Pg.79] [Pg.133] [Pg.67] [Pg.49] [Pg.337] [Pg.152] [Pg.101] [Pg.146] [Pg.284] [Pg.29] [Pg.625] [Pg.49] [Pg.6] [Pg.209] [Pg.322] [Pg.340] [Pg.121] [Pg.300] [Pg.1324] [Pg.219]

See also in sourсe #XX -- [ Pg.320 ]

See also in sourсe #XX -- [ Pg.320 ]

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Identification Screening

Lead identification

Screen virtual

Screening virtual

Successful Identification of Novel Leads Through Virtual Screening

Virtual screening lead identification