Vinca libanotica

The aerial parts of Lebanese Vinca libanotica Zucc. appear to contain 16 alkaloids, of which 12 have so far been isolated these include, in the present group, vincamajine (the major alkaloid), picrinine, quebrachidine, vincamidine, vin-camidine hydrate, herbamine, and herbadine. The structures earlier proposed for herbamine and herbadine have now been shownto be incorrect, and on the basis of mass spectral and 220 MHz n.m.r. data, have been shown to be (113) and (114) respectively. The n.m.r. spectrum of herbamine is very similar to that of vincamajine except for the non-equivalence of the C-21 protons in herbamine. Inspection of models, confirmed by n.m.r. studies in the ajmaline-2-epiajmaline series, indicates... 

Vincoline was first isolated by Svoboda et al. from Catharanthus roseus (L.) G. Doh (44), then by Farnsworth et al. from C. lanceus (45), and by Aynilian et al. from Vinca libanotica Zucc. (46). 

Vinca herbaeea Waldst et Kit. var. libanotica (Zuoo.) Piehon... 

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