Vimentin primary site

MELANOMA The Small intestine is a common metastatic site of cutaneous melanomas primary melanomas arise rarely in the gastrointestinal tract and are most common in the anorectum and esophagus. Their immuno-phenotype is identical to their cutaneous counterparts they stain with vimentin, S-100, HMB-45, melan-A, and tyrosinase (Fig. 14.35). " As noted earlier, c-kit may be positive in a subset of melanomas. 

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