Vesicles polymer-encased

Fukuda H, Diem T, Stefely J, Kezdy FJ, Regen SL. Polymer-encased vesicles derived from dioctadecyldimethylammonium methacrylate. J Am Chem Soc 1986 108 2321-2327. 

Regen SL, Shin JS, Yamaguchi K. Polymer-encased vesicles. J Am Chem Soc 1984 106 2446-2447. 

Polymeric phospholipids based on dioctadecyldimethylammonium methacrylate were formed by photopolymerization to give polymer-encased vesicles which retained phase behavior. The polymerized vesicles were more stable than non-polymerized vesicles, and permeability experiments showed that vesicles polymerized above the phase transition temperature have lower permeability than the nonpolymerized ones [447-449]. Kono et al. [450,451] employed a polypeptide based on lysine, 2 aminoisobutyric acid and leucine as the sensitive polymer. In the latter reference the polypeptide adhered to the vesicular lipid bilayer membrane at high pH by assuming an amphiphilic helical conformation, while at low pH the structure was disturbed resulting in release of the encapsulated substances. 

Following route 3, S. L. Regen 111 > built polymer-encased vesicles by the photo-polymerization of DODAM (dioctadecyldimethylammonium methacrylate)... 

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