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Vertex pharmaceuticals

Elaine K. Kolaczkowski Vertex Pharmaceuticals, Cambridge, Massachusetts, U.S.A. [Pg.9]

Vertex Pharmaceuticals, Inc., Cambridge, Massachusetts, US.A. Steven A. Kates... [Pg.181]

Figure 9.1 A molecular model showing HIV-1 protease complexed with an inhibitor, amprenavir. (This figure kindly provided by Vertex Pharmaceuticals Inc.)... Figure 9.1 A molecular model showing HIV-1 protease complexed with an inhibitor, amprenavir. (This figure kindly provided by Vertex Pharmaceuticals Inc.)...
Finally, I am grateful to Vertex Pharmaceuticals Inc. for supplying the photograph that graces the cover of this book. [Pg.424]

Vertex Pharmaceuticals RiboTargets GeneFormatics TRIAD Therapeutics Integrative Proteomics Metabometrix Novaspin Biotech ... [Pg.110]

Jonathan M. Blackburn Department of Biotechnology, University of the Western Cape, Cape Town, South Africa Procognia Ltd, Maidenhead, UK Paul R. Caron Head of Informatics, Vertex Pharmaceuticals,... [Pg.291]

Vertex Pharmaceuticals, San Diego, CA 92121, USA Fredrick VanGoor sd.vrtx.com... [Pg.91]

D.M. Armistead et al, US Patent 6,967,214 (November 22, 2005) Assignee Vertex Pharmaceuticals Incorporated Utility Immunosuppressants Following Organ Transplant Procedures... [Pg.384]

Takeda Pharmaceutical Company Limited Vertex Pharmaceuticals Incorporated Warner Lambert Company Wyeth... [Pg.671]

Then the leader of that project, Irving Sigal, was killed on the Pan Am flight that exploded over Lockerbie, Scotland. Another clutch of scientists bolted to form their own biotech, which they named Vertex Pharmaceuticals. [Pg.199]

Figure 2 Small-molecule inhibitors of caspases. (a) Schematic of a typical caspase inhibitor (b) caspases substrate specificities preferred amino acids in PI -P4 positions (c) chemical structure of PAC-1, procaspase-3 activator (EC50 of 0.22 uM) (d) low-nanomolar inhibitors of caspases-3 and -7 (compound 1) and caspases-3, -7 and -9 (compound 2) (e) caspase-1 peptidomimetic inhibitor VX-740 or pralnacasan from Vertex Pharmaceutical (Cambridge, MA) (f) peptidomimetic irreversible oxamyl dipeptide pan-caspase inhibitor IDN-6556 from IDUN Pharmaceuticals and (g) caspase-3 inhibitor. Figure 2 Small-molecule inhibitors of caspases. (a) Schematic of a typical caspase inhibitor (b) caspases substrate specificities preferred amino acids in PI -P4 positions (c) chemical structure of PAC-1, procaspase-3 activator (EC50 of 0.22 uM) (d) low-nanomolar inhibitors of caspases-3 and -7 (compound 1) and caspases-3, -7 and -9 (compound 2) (e) caspase-1 peptidomimetic inhibitor VX-740 or pralnacasan from Vertex Pharmaceutical (Cambridge, MA) (f) peptidomimetic irreversible oxamyl dipeptide pan-caspase inhibitor IDN-6556 from IDUN Pharmaceuticals and (g) caspase-3 inhibitor.
Siegmund B, Zeitz M. Pralnacasan (vertex pharmaceuticals). IDrugs 2003 6 154-158. [Pg.180]

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See also in sourсe #XX -- [ Pg.78 , Pg.199 ]

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See also in sourсe #XX -- [ Pg.10 , Pg.165 , Pg.199 , Pg.230 , Pg.250 , Pg.307 , Pg.490 ]



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