Vascular prostheses prosthesis

Figure 26. Reconstruction of the tunica intima on the inner surface of a clinically used polyethylene terephtalate vascular prosthesis. A non-modified inner surface of the prosthesis, B immobilization of defined assemblies of protein molecules (e.g., collagenfiarninin or collagen+fibrin) on the inner surface of the graft, C immunofluorescence of von Willebrand factor, a marker of the identity a differentiation of vascular endothelial cells, in human saphenous vein endothelial cells in cultures on the inner surface of a prosthesis coated with collagen and larninin, D detail of a layer of endothelial cells growing on a layer of collagen and fibrin. Note well developed talin-containing focal adhesion plaques. A, B conventional optical microscope, C, D confocal microscope Leica DM 2500 [30,31].

BLOOD-VESSEL WALL RELATIONSHIPS (INTERACTIONS OF FLOWING BLOOD WITH THE VESSEL/VASCULAR PROSTHESIS WALL)... 

Fig. 4. Vascular prosthesis made of woven polytetrafluoroethylene. The photograph shows the great ability of the fabric to fray.

Fig. 5. Vascular prosthesis made of micoporous polytetrafluoroethylene, also known as expanded polytetrafluoroethylene.

In a more recent paper [160], Urry et al. reported that x20-poly (GGAP) was nonadhesive to both bovine ligamentum nuchae fibroblast and human umbilical vein endothelial cells (HUVECs), even in the presence of serum. Urry et al. interpreted this behavior in terms of their hydrophobicity scale. They suggested that x20-poly[50(GGAP), (GRGDSP)], for example, could provide the inner lamina for a vascular prosthesis. 

Noishiki, Y., Tomizawa, Y., Yamane, Y., and Matsumoto, A. 1996. Autocrine angiogenic vascular prosthesis with bone marrow transplantation. Nat. Med. 2 90-93. 

Disadvantages include the twofold anastomosis and the use of a plastic vascular prosthesis with the associated higher rate of thrombosis of 15 — 30%. 

The concentration of dissolved oxygen in water at 25°C in contact with air is 8 ppm (39). The concentration of dissolved oxygen in blood (40) compares favorably to this value, at 4.3 ppm. The major part of 02, about 280 ppm in the blood, however, is bound with hemoglobulin, and is not considered available for reaction with the inner walls of a vascular prosthesis. Deaeration of the protein solutions for electrochemical measurements was not carried out for the same reason cited in the literature (12, 13) that is, denaturation of protein occurs with deaeration. 

Sipehia, R., G. Martucci, ). Lipscombe, Transplantation of human endothelial cell monolayer on artificial vascular prosthesis the effect of growth-support surface chemistry, cell seeding density, ECM protein coating, and growth factors. Artif. Cells Blood Substit. Immobil. Biotechnol., 1996, 24(1) 51-63. 

Greisler, H. P., Pham, S. M, Endean, E. D. et al.. Relationship between changes in biomechanical properties and cellular ingrowth in absorbable vascular prosthesis, ASAIO Abstracts, 16, 25, 1987. 

Greisler, H. P, New Biologic Synthetic Vascular Prosthesis, R.G. Landes, Austin, TX, 1991. 

Bowald, S., Busch, C. and Eriksson, L, Absorbable material in vascular prosthesis A new device, Acta. Chir. Scand., 146, 391, 1980. 

Zenni, G. C., Gray, J. L., Appelgren et al., Modulation of myofibroblast proliferation by vascular prosthesis biomechanics, ASAIO., 39, M496, 1993. 

G.J. Wilson, D.C. MacGregor, P. Klement, J.P. Dereume, B.A. Weber, A.G. Binnington, L. Pinchuk, The composite Corethane/ Dacron vascular prosthesis. Canine in vivo evaluation of 4 mm diameter grafts with 1 year follow-up, ASAIO Trans. 37 (3) (1991) M475-M476. 

T. Okoshi, G. Soldani, M. Goddard, P.M. Galletti, Very small diameter polyurethane vascular prosthesis with rapid endotheliahzation... 

Figure 2.5 (a) Umbilical cord with central vein and smaller snrronnding arteries (left panel). This is clearly demonstrated on the microscopic view (right panel) (b) human umbilical cord vein manufactured as a vascular prosthesis including an outer Dacron mesh (c) retention of graft architecture with glutaraldehyde processing at 2 weeks, 8 months, and 2 years. 

Dardik H, Ibrahim IM, Dardik I. Evaluation of glutaraldehyde-tanned human umbilical cord vein as a vascular prosthesis for bypass to the popliteal, tibial, and peroneal arteries. Surgery 1978 83 577-88. 

Mrowczynski, W., Mugnai, D., de Valence, S, Tille, J.C., Khabiri, E., Cikirikcioglu, M. et al. (2013) Porcine carotid artery replacement with biodegradable electrospun poly-e-caprolactone vascular prosthesis. J. Vase. Surg., 59 (1), 210-219. 

Tibial Plateau Replacements Vascular Attachment Prosthesis... 

Y. Douville, Evaluating the Dialine vascular prosthesis knitted from an alternative source of polyester yarns . Journal of Biomedical Materials Research, vol. 29, no. 5, pp. 595-610, May 1995. 

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