Variceal bleeding primary prophylaxis

Treatment Recommendations Variceal Bleeding-Primary Prophylaxis... [Pg.699]

Boyer TD Primary prophylaxis for variceal bleeding Are we there yet Gastroenterology 2005 128 1120. [PMID 15825093]... [Pg.219]

Imperiale, T.F., Chalasani, N. A metaanalysis of endoscopic variceal ligation for primary prophylaxis of esophageal bleeding. Hepatology 2001 33 1003-1004... [Pg.370]

Merkel, C., Marin, R., Enzo, E., Donada, C., Cavallarin, G., Torboli, P, Amodio, P., Sebastianelli, G., Sacerdoti, D., Felder, M., Mazzaro, C., Beltrame, R, Gatta, A. Randomised trial of nadolol or with isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis. Lancet 1996 348 1677-1681... [Pg.370]

Saab, S., DeRosa, V., Nieto, J., Durazo, F., Han, S., Roth, B. Costs and clinical outcomes of primary prophylaxis of variceal bleeding in patients with hepatic cirrhosis A decision analytic model. Amer. J. Gastroenterol. 2003 98 763-770... [Pg.371]

Step 3 Reduction in portal pressure (42, 74, 113, 115) increased at an early stage, and prevention of variceal bleeding as part of a primary prophylaxis are important measures. In our experience, the development of pulmonary hypertension can be delayed (or even prevented), (s. p. 337) This might be achieved, for example, by administering (5.) molsidomine and (<5.) beta blockers (in combination with spironolactone as in Step 1). The frequent occurrence of portal colopathy (30-40%), even with colitis-like abnormalities, can be reduced by propa-nolol. (21,158) A combination of isosorbide-5-mononi-trate with nadolol has been successful in cases where treatment with beta blockers alone did not prove effective. (s. pp, 258, 355)... [Pg.743]

The management of varices involves three strategies (a) primary prophylaxis (prevention of the first bleeding episode) (b) treatment of acute variceal hemorrhage and (c) secondary prophylaxis, prevention of rebleeding in patients who have previously bled. °... [Pg.699]

Teran JC, Imperiale TF, Mullen KD, et al. Primary prophylaxis of variceal bleeding in cirrhosis A cost-effectiveness analysis. Gastroenterology 1997 112 473-482. [Pg.711]

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