LeBel-van’t Hoff Theory

It should also be mentioned that the predictions based on the van t Hoff-LeBel theory of stereochemistry were tested and ultimately substantiated by a plethora of experimental evidence, as, for example the preparation of optically active derivatives of allenes like 72 and quaternary ammonium salts of the type 73. 

This then, is the van t Hoff-LeBel Theory of Stereo-isomerism known also as the Theory of the Asymmetric Carbon Atom or as the Tetrahedral Theory. The theory is supported by a large number of facts and has been fruitful in leading to new discoveries. We shall find cases of stereo-isomerism in several of the classes of compounds which we shall study and some of our most common substances, such as lactic acid,... 

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