Validation of effective preservation

Adequate preservation is said to guarantee effective protection if, during storage and product use, both as instructed or in any other foreseeable manner, it suffers no spoilage, or the growth of undesirable, or pathogenic organisms. 

To fulfil these requirements, not only the selection of preservative type and concentration needs careful consideration during formulation development, but also the type and extent of potential microbial influences which might adversely effect the quality of the finished product quality. The microbial quality of raw materials is a particularly important factor, but the provision of comprehensive production instructions, covering the processing of preservatives and plant hygiene, from the receipt of raw materials to the dispatch of the end product is also vital. 

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