Urine, analysis spray applicators

Applicators, mixers, loaders, and others who mix, spray, or apply pesticides to crops face potential dermal and/or inhalation exposure when handling bulk quantities of the formulated active ingredients. Although the exposure periods are short and occur only a few times annually, an estimate of this exposure can be obtained by quantifying the excreted polar urinary metabolites. Atrazine is the most studied triazine for potential human exposure purposes, and, therefore, most of the reported methods address the determination of atrazine or atrazine and its metabolites in urine. To a lesser extent, methods are also reported for the analysis of atrazine in blood plasma and serum. 

The aforementioned series of reactions provides a basis for a colorimetric analytical method for Compound 118 in which the commonly used agricultural chemicals do not interfere. The procedure described herein permits the estimation of as little as 10 micrograms of Compound 118, and has been successfully applied to the analysis of this insect toxicant in insecticidal dusts, in film residues on glass and paper, in human and animal urine, and in mixture with other insecticides. Application of this procedure to the determination of Compound 118 in milk and in spray and dust residues on plants appears promising. 

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