Urea, Amidino

In contrast, 1-substituted biguanides are hydrolysed to N-amidino-N -substituted ureas (LXXVII) (498), the structure of which is confirmed by the unequivocal s mthesis of their isomers (LXXVIII) by acid hydrolysis of the appropriate cyanoguanidine. 

Proclavaminate amidino hydrolase (PAH) is one of a number of enzymes that are Mn activated and whose amino acid sequence shows strong homology with arginase. PAH catalyzes the hydrolysis of a guanidino group to give proclavaminate and urea (Equation (8)) ... 

This enzyme [EC 3.S.3.4], also called allantoate amidino-hydrolase, catalyzes the hydrolysis of allantoate to produce (-)-ureidoglycolate and urea. The enzyme can also catalyze the hydrolysis of (+)-ureidoglycolate to generate glyoxylate and urea. 

Pyrolysis of amidino dichlorides (from urea and phosgene) to carbodiimide [67],... 

X = S) is excluded on the basis of the reduction of the corresponding ureas (143) to the known 3-aryl-l-(isopropylideneamino-amidino)ureas (143a R = Ph). In the absence of rearrangement, the condensation products of isocyanates and nitroguanidine may thus be formulated as nitramines (143), and, by analogy, their sulfur analogs as 139.141... 

Amidino-3-nitrourea. See Nitroguanylurea under Guanyl urea... 

A series of amidino ureas synthesised in Poland, and exemplified by nitro-guanil (78), were introduced as substitutes for proguanil because of their more favourable chemotherapeutic index [275, 276]. Although proguanil is... 

Dry the resulting polymer in vacuo to yield PEG-bound A,(lV -rert-butoxy-carbonyl- amidino)urea in 98% yield. 

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