Tyrosine residues fructose-1,6-diphosphatase

The specific inhibition of D-fructose 1,6-diphosphatase by AMP decreases if the pH of the solution moves399 to above 9. Inhibition by AMP and catalytic activity can be lost by acetylation of the tyrosine residues with 1-acetylimidazole. The presence of substrate or allosteric effectors protects the tyrosine from acetylation.400 Pyridoxal phosphate can also desensitize the enzyme by forming a Schiff base with L-lysinyl residues401 this indicates some participation of L-lysinyl residues in allosteric regulation.401,402... 

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See also in sourсe #XX -- [ , , , , ]

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