Type of Killing Action

The PD of antimicrobial dmgs against microorganisms comprises three main aspects spectmm of activity, bactericidal and bacteriostatic activity, and the type of killing action (i.e., concentration-dependent, time-dependent, or co-dependent). Each of these is discussed below. Also described are the PD indices—minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)—and the mechanisms of action of antimicrobial drugs. 

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