Two-Component Domino Reaction under Microwave Heating

Two-Component Domino Reaction under Microwave Heating 

Inspired by the importance of nitrogen-containing heterocycles in studying bioactive substances, such as pharmaceuticals and agricultural chemicals. West and 

Prakash and coworkers reported a domino method of hydrolysis/dehydro-halogenation/Heck coupling to synthesize styrene sulfonate salts 21 in up to 

Carboxylic acids 38 were successfully converted into methylthiomethyl (MTM) esters 39 under microwave-assisted condition, as reported by Zimmerman et al. 

Poly-substituted 3-benzylquinoxaHn-2(lH)-ones 54, benzo[d]imidazoles 55, and P-amino dipeptides 56 were all prepared using 4-arylidene-2-phenyloxazol-5-ones 52 and a large number of diverse ortho-diamines 53 in a highly selective manner. 

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