Tuberculosis Caseation

The tuberculous primary complex in the liver with caseation of the associated hepatic hilar lymph nodes may become the source of spread causing early systemic generalization. Given the clinical picture of a coarse-nodular or a miliary tuberculosis, this may result in the death of the newborn child. 

Tuberculosis can involve any region of the CNS and its coverings. The disease usually causes granulomatous inflammation with or without caseating necrosis, meningitis, or arteritis. The extensive time required to grow mycobacteria invites preliminary testing with IHC, PCR assay, or acid-fast stains. ... 

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