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Troponin head structure

The actual picture of the troponin head, however, could not have been fully anticipated before the recent crystal structures of the Ca2+-activated cardiac (not shown) and skeletal troponin head region (Fig. 6C and D), both of which contain all three subunits (Takeda et al., 2003) (Vinogradova et al., 2005). To be sure, one can easily recognize the previously observed or predicted features such as the IT coiled-coil in these structures, as well as the contacts made between the TnC lobes and... [Pg.137]

As in the case of the myosin head, knowledge of actin filament structure, or thin filament structure as it is termed when tropomyosin and troponin are present, also progressed rapidly when the structure of the globular actin (G-actin) monomer was determined by protein crystallography in... [Pg.34]

Schematic diagram of the structure of myosin. This muscie protein consists of a rodiike coii of a-heiices with two giobuiar heads, aiso composed of protein, attached to myosin at its C-terminus. in muscie, myosin moiecuies are assembied into thick fiiaments that aiternate with thin fiiaments composed of the proteins actin, troponin, and tropomyosin. Working together, these fiiaments aiiow muscies to contract and reiax. Schematic diagram of the structure of myosin. This muscie protein consists of a rodiike coii of a-heiices with two giobuiar heads, aiso composed of protein, attached to myosin at its C-terminus. in muscie, myosin moiecuies are assembied into thick fiiaments that aiternate with thin fiiaments composed of the proteins actin, troponin, and tropomyosin. Working together, these fiiaments aiiow muscies to contract and reiax.
Figure 4.7. Structural model of proteins complex, consisting from myosin head (HMM-Sl), actin (A), tropomyosin (TM), and the three troponins (In - T, I, and C, respectively), (a) "blocked" position - relaxation (b) "free" access of HMM-Sl to actin filaments - contraction. Figure 4.7. Structural model of proteins complex, consisting from myosin head (HMM-Sl), actin (A), tropomyosin (TM), and the three troponins (In - T, I, and C, respectively), (a) "blocked" position - relaxation (b) "free" access of HMM-Sl to actin filaments - contraction.

See other pages where Troponin head structure is mentioned: [Pg.140]    [Pg.140]    [Pg.138]    [Pg.139]    [Pg.140]    [Pg.140]    [Pg.543]    [Pg.208]    [Pg.718]    [Pg.10]    [Pg.24]    [Pg.123]    [Pg.135]    [Pg.137]    [Pg.144]    [Pg.147]    [Pg.148]    [Pg.162]    [Pg.196]    [Pg.20]    [Pg.20]    [Pg.33]    [Pg.42]    [Pg.309]    [Pg.53]    [Pg.63]    [Pg.72]    [Pg.73]    [Pg.599]    [Pg.427]    [Pg.469]    [Pg.305]   
See also in sourсe #XX -- [ Pg.140 ]




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