Triton WR1339

De Ferreyra, E. C., De Fenos, O. M., and Castro, J. A., Modulation of galac-tosamine-induced liver injury by some amino acids or Triton WR1339, Toxicol. 

VLDL secretion can also be studied in vivo by injection of mice or rats with the detergent Triton WR1339 or poloxmer. These compounds block the lipolysis of TG-rich lipoproteins in plasma so that the amount of plasma apo B-containing lipoproteins reflects only the secretion of apo B, in the absence of lipolysis. This methodology has some limitations, primarily because neither detergent is specific for blocking VLDL lipolysis (J.T. Billheimer, 2005). 

Leighton, F., Poole, B., Beaufay, H., Baudhuin, P., Coffey, J. W., Fowler, S., and DeDuve, C., 1968, The large-scale separation of peroxisomes, mitochondria and lysosomes from the livers of rats injected with Triton WR1339, J. Cell Biol. 37 482-513. 

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