1,3,5-Trithiane lithiation

Trithiane 266 has been successively lithiated and allowed to react with compounds 269 to give permethylated mono-, di- and tri-fulvathianes 270-272448. 

Amino acid-based dithiazines 281 were lithiated and allowed to react with benzaldehyde, giving products 282 in good yields but with low diastereoselectivity (Scheme 72)451. These adducts underwent externally sensitizer photofragmentation with quantum efficiency comparable to the parent dithiane and trithiane adducts. 

Trithianes (74) undergo lithiation with an equivalent of /i-butyllithium to yield the 2-Iithio derivatives, which substances undergo the usual reactions (equation 67) as with 2-lithio-l,3-dithianes. Since additional active hydrogens are present in 1,3,5-trithianes, dimethyladon has been observed in some cases. ... 

Lactones, addition of thiols 769 Lead, thiol derivatives 748, 749 Lipoic acid 637-639 Lithiation, of 1,3-dithiane 536 of 1,3,5-trithiane 546, 547 2-Lithio-l,3-dithianes, for preparation of 1-deuterioaldehydes 547 for preparation of orthothioformate 547... 

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