Triphenylmethyl group deprotection

Amines can also be protected from unwanted acylation or from twofold alkylation by alkylation with a sterically demanding group that is amenable to selective removal after completion of the synthesis. The most commonly used groups for this purpose are triphenylmethyl derivatives. Amines are readily tritylated using trityl chloride in the presence of a tertiary amine. Deprotection is achieved by treatment with dilute... 

Another biocompatible and biodegradable polymer, chitosan, was converted into a multifunctional macroinitiator for the ZLL-NCA polymerization. Initially, the amine groups of chitosan were protected with phthalic anhydride, followed by triphenylmethyl protection of the 6-CH2OH groups. The amine groups were deprotected by hydrazine and used to... 

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