Triphase catalysis chemistry

Phase transfer catalysis is a significant advance in preparative organic chemistry, but there is a practical limitation—phase transfer agents sometimes stabilize emulsions, which make product recovery difficult. A variation of the technique, called triphase catalysis, involves bonding the phase transfer agent to a support, such as a gel-form polymer (see 14.2.4.1) . If the polymer has an affinity for boA liquid phases, the phase... 

R. A. Sawicki, Triphase Catalysis in Organometallic Anion Chemistry, in Phase Transfer Catalysis New Chemistry Catalysts, and Applications (Ed. Ch. M. Starks), ACS Symposium Ser. No. 326, American Chemical Society, Washington, DC, USA, 1987, Chapter 12, p. 143. 

In triphase catalysis, solvated resin supports are important carriers for solid-phase organic synthesis in combinatorial chemistry. The physical properties of resin, resin swelling, dynamic solvation, and solvated supports are important factors in affecting the synthesis. However, these factors are also affected by solvent. Selective solvation of resin alters the local reactivity and accessibility of the bound substrate and the mobility of the entrapped re-... 

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