Triosephosphate isomerase properties

Normal mode analysis of the mechanical properties of a triosephosphate isomerase-barrel protein suggests that the region between the secondary structures plays an important role in the dynamics of the protein. The beta-barrel region at the core of the protein is found to be soft in contrast to the helical, strand and loop regions [62]. A detailed discussion of other properties of proteins is mechanically highly non-linear systems is given by Kharakoz [63]. 

Lambeir, A.-M., Opperdoes, F. R. and Wierenga, R. K. (1987) Kinetic properties of triosephosphate isomerase from Trypanosoma brucei a comparison with the rabbit muscle and yeast enzymes. Eur. J. Biochem. 168 69-74. 

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