2.4.5- trichlorobiphenyl

Along with degree of chlorination another determinant of PCB metabolism in fish is species. Green sunfish and goldfish rapidly metabolize 2,2, 5-trichlorobiphenyl whereas bullheads and rainbow trout metabolize it slowly (26,29). There is little evidence for PCB metabolism in brook trout fed 4-chloro-, 4,4 -dichloro-, 2,2, 5,5 -tetrachloro- or 2,2, 4,4, 5,5 -hexachloro-biphenyl (31) and this was confirmed in rainbow trout by less than 1% of 2,2, 5,5 -tetrachlorobiphenyl accumulated being recovered as polar metabolites (25). 

Elimination. Rate that PCBs are eliminated by fish is strongly influenced by their rate of metabolism. Figure 7 shows concentration of PCB in green sunfish after being exposed to a high or low dose of 2,2, 5-trichlorobiphenyl or 2,2, 4,5,5r-pentachlorobiphenyl on day 0 and again on day 9 (26). Of these... 

Kp were calculated by averaging the partitioning data collected after 2 hr in experiments conducted in the absence of OH. Equation (6.130) may be employed to model partitioning kinetics over short time intervals, but applying the particles used in these experiments as equilibrium models may not adequately predict partitioning over extended time intervals for many types of particles. Partitioning data and reaction rate constants calculated for 2,2, 5-trichlorobiphenyl and 2,2, 4,4, 5-PeCIBp by Sedlak and Andren (1994) are shown in Table 6.6. 

Partitioning Data and Reaction Rate Constants Calculated for 2,2, 5-Trichlorobiphenyl and 2,2, 4,4, 5-Pentachlorobiphenyl... 

Common Name 2,2,5-Trichlorobiphenyl Synonym PCB-18, 2,2,5-trichloro-l,r-biphenyl Chemical Name 2,2,5-trichlorobiphenyl CAS Registry No 37680-65-2 Molecular Formula C12H7C13 Molecular Weight 257.543 Melting Point (°C) ... 

Li MH, Hansen LG. 1995. Uterotropic and enzyme induction effects of 2,2, 5-trichlorobiphenyl. Bull Environ Contam Toxicol 54(4) 494-500. 

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