Trichloroacetyl bromide

A well-stirred suspension of 1-phenylcyclohexene (3.75 g, 23.7 mmol) and freshly prepared activated Zn (3.9 g, 59.3 mmol) in anhyd Et20 (150 mL) was brought to reflux. Trichloroacetyl bromide (16.1 g, 71.1 mmol) in anhyd Et20 (70 mL) was added dropwise to the stirred suspension over a period of 4-6 h while additional Zn (14.7 g, 225 mmol) was added portionwise over the same period. Refluxing was continued for an additional 2-4 h. The mixture was filtered through Celite and the filtrate washed with several aliquots of H20. After drying (MgS04), the solvent was removed in vacuo and the crude dichlorocyclobutanone 1 was subjected to reductive dechlorination as follows to a solution of crude ketone 1 in HOAc was added... 

Gentiotetraose, an all ()-(I —>6)-l inked tetramer of glucose was selectively prepared by Gagnaire and coworkers (Scheme 1.4).19 6-0-Trichloroacetylated glucosyl bromide 27 was attached to succinoylated 2% crosslinked polystyrene. After selective... 

Thiocarbonyl tetrachloride, i6, 21 Thionyl chloride, 45, 16, 98 Thiophosgene, 45, 21 Thiophosphoryl chloride, reaction with methylmagnesium bromide to yield tetramethylbiphosphine disulfide, 45,102 Toluenesulfonybromide, 46, 88 Trichloroacetyl fluoride, 46, 6 1,1,3-Trichloiio- -nonane, 46,104 Tricyclo[2.2.1.0 ]heptan-3-ol, 45,... 

The influences of -allyl, benzyl, acetyl, trichloroacetyl and levullnoyl substituents at 0-3, 4 or 6 on the a,S ratio in the products of silver silicate or silver zeolite activated coupling of 2- -benzyl-a-D-gluco- and manno-pyranosyl bromide derivatives with the anhydrides (24) and (25) have been examined. Highest 3 a-... 

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