Triazolo benzoxazepine

Treatment of the 1,2,4-triazino[5,6-benzoxazepine derivatives (631) with an excess of methyl iodide affected methylation and intramolecular rearrangement to give the mesoionic l,2,4-triazolo[l,6-c] quinazolinone (632) (73MI1). 

Intramolecular cycloaddition of an azide to an acetylenic bond offers a route to the synthesis of [l,2,3]triazolo[l,5-a][4,l]benzoxazepines (Scheme 16) <94H(38)291>. Considering the ready availability of the starting material (isatoic anhydrides and propargyl alcohols) this offers an attractive route to these compounds. 

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