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Triazole and triazoline-ring formation

In a study aimed at optimizing the 1,3 -dipolar cycloaddition process for DNA analysis and immobilization, Ju found that the cycloaddition of non-bioconjugated azides can be carried [Pg.167]

Kinetic data regarding the 1,3-dipolar cycloaddition of phenyl azide with norbornene in various solvents to give triazoline 98 were reported by Engeberts (Table 5.8). A high reaction rate enhancement (a factor of 53 relative to n-hexane) was observed when the reaction was performed in water containing 1% of l-cyclohexyl-2-pyrrolidinone (NCP). [Pg.169]


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1.2.3- Triazoline ring

Ring formation

Triazole ring

Triazoles formation

Triazoline

Triazolines formation

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