Triazolate complexes structural properties

Groessl M, Reisner E, Hartinger CG, Eichinger R, Semenova O, Timerbaev AR, Jakupec MA, Arion VB, Keppler BK (2007) Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuC14L(S-dmso)ruthenate(in)] (L = imidazole, indazole, 1, 2, 4-triazole, 4-amino-1, 2, 4-triazole, and 1-methyl-l, 2, 4-triazole) aquation, redox properties, protein binding, and antiproliferative activity. J Med Chem 50 2185-2193... 

The perfluoro-1,2,4-triazoles are known to be effective ligands. For instance, a number of charge neutral Os(II) pyridyl-l,2,4-triazolate complexes with either bis(diphenylphosphino)methane 93 or ct>l,2-bis(diphenylphosphino)ethene 94 chelates were synthesized, and their structural, electrochemical, photophysical properties and thermodynamic relationships were established [89, 90], Chi, Carty et al. synthesized 6-(3-trifluoromethyl-l,2,4-triazolyl)-2,2 -bipyridine and built up on this basis tridentate 6-azolyl-2,2 -bipyridine chelate complex compounds of Ga and In 95 [91],... 

The acid-base properties of the ground and excited states of [Ru(bpy)2(im)2] and [Ru(bpy)2(l,2,4-triazole)2] have been investigated. Both complexes are stronger acids in the excited than the ground states." Representative triazoles, L or HL, have been incorporated into the complexes [Ru(bpy)2L]"" (n = 1 or 2). Electronic spectroscopic and electrochemical properties have been reported all the ligands are weaker tt acceptors than bpy." " The crystal structures of... 

Arion VB, Reisner E, Fremuth M, Jakupec MA, Keppler BK, Kukushkin VY, Pombeiro AJL (2003) Synthesis, X-ray diffraction structures, spectroscopic properties, and in vitro antitumor activity of isomeric (1H-1, 2, 4-Triazole)Ru(III) complexes. Inorg Chem 42 6024—6031... 

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