Transfer Phenomena in Chromatography

2 Axial Dispersion and Mass Transfer Resistance in Porous Media.240 

2 Importance of the Mobile Phase Viscosity in Preparative Chromatography. 264 

3 Calculation of the Inlet Pressure in the Case of a Variable Viscosity.266 

4 Feed Concentration, Mobile Phase Viscosity and Inlet Pressure at Constant Flow 

Chromatography is a powerful separation method because it can be carried out easily under experimental conditions such that the two phases of the system are always near equilibrium. This is because the kinetics of the mass transfers between these phases is usually fast. The separation power of a column, under a given set of experimental conditions, is directly a function of the rate of the mass transfer kinetics and of the axial dispersion coefficient. The scientists involved in the development of stationary phases for chromatography have produced excellent packing materials that permit the achievement of a very large number of equilibrium stages (i.e., theoretical plates) in a column. Thus, as we show later in Chapters 10 and 11, the thermodynamics of phase equilibria is often the main 

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