Transcription factor GATA family

NFAT2 plays a key role in the development of the embryo s heart. In the precursor cells, there is a temporal and spatial specific expression of NFAT2, which directs the formation of the valves and the septum in the heart. In the adult heart, NFAT proteins also cooperate with transcription factors of the GATA and MEF2 families to regulate cardiac muscle hypertrophic responses. 

The serpent (srp) gene encodes a transcription factor of the GATA family and is required for the formation of two different mesodermal cell types fat body and he-mocytes. 

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