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Transcription Activator-Like Effector

Sun, N., Zhao, H., 2013. Transcription activator-like effector nucleases (TALENs) a highly efficient and versatile tool for genome editing. Biotechnol. Bioeng. 110,1811-1821. [Pg.495]

ILIO transcripts to allow their detection even without ex vivo restimulation (Aguado et al 2002). Upon activation by phorbol-12-myristate-l 3-acetate (PMA) and iono-mycin, IL5, IL13 and IFNy transcripts were additionally detected, and close to 80% of the CD4 T cells expressed high levels of intracytoplasmic IL4. Thus, over the first weeks of life and in the absence of deliberate antigenic stimuU, the CD4 ap T cells that expanded in mice deployed a Th2-like effector... [Pg.95]

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Activated transcription

Activators transcription

Effector

Transcription activation

Transcription activator-like effector nucleases

Transcriptional activation

Transcriptional activator

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