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Transamination of cytosine

Shapiro, R., and Weisgras, J.M. (1970) Bisulfite-catalyzed transamination of cytosine and cytidine. Biochem. Biophys. Res. Comm. 40, 839-843. [Pg.1113]

A comparative evaluation of methylamine, methylamine/anunonium hydroxide and ammonium hydroxide/ethanol for the deprotection of oligonucleotides has also been undertaken. In order to avoid the possible transamination of cytosine when benzoyl protection is employed for the amino group an acetyl protected monomer was used instead. Methylamine or methylamine/ammonium hydroxide mixtures were found to liberate the oligoribonucleotide at room temperature in 90 minutes and improve the yield of the desired product. [Pg.195]

See also in sourсe #XX -- [ Pg.55 , Pg.457 , Pg.974 ]

See also in sourсe #XX -- [ Pg.44 , Pg.357 , Pg.645 ]

See also in sourсe #XX -- [ Pg.44 , Pg.357 , Pg.645 ]



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