Toxicity of Blister Agents

Lewisite, when used as a chemical warfare agent, affects the eyes, respiratory tract and skin, these being the parts most exposed to the gas. Furthermore, Lewisite has lipophilic properties and penetrates easily through the skin [120]. 

Compound LD50 or LC50 LDlo or LClo Additional effects 

2-Diisopropyl- Rat oral, 860mgkg [91] - Rabbit skin irritant, severe 

Diethyl methylphos- Mouse ip, 2240mgkg [94] open, severe [92] 

Diethyl dimethyl Rabbit skin, 7.1 mgkg [90] pyrophospho-nate 

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