Toxicant-Induced Lung Injury, Remodeling, and Repair

3 TOXICANT-INDUCED LUNG INJURY, REMODELING, AND REPAIR 

A number of factors determine whether tissue in the lung parenchyma is successfully repaired after injury or whether an inflammatory response progresses to a pathologic outcome. As mentioned previously, the alveolar region is especially vulnerable to damage due to the delicate architecture of the type I epithelium and blood capillary endothelial membranes. An appropriate balance of catabolic and 

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