Torus accelerator

By the covalent addition of two imidazole groups to the cyclodextrin torus, artificial ribonucleases have been formed, and these have notable specificity with respect to both substrates and products (Breslow, 1983). Similar accelerations and specificities were found by coupling pyridoxamine covalently to a cyclodextrin to give an artificial transaminase. The accelerations produced by these models are only about 200-fold, but work in progress holds out hope for obtaining far greater velocities (Breslow, 1983). 

Fig. 5.11 Numerical simulation of bubble under forced vibration. Results for Bo = 0.7 based on the imposed acceleration for a 4 mm diameter air bubble inside water. Initial shape is sphere, but different shapes are observed and breakup to a torus shape is achieved...

Torus-shaped a-cyclodextrin, which is a molecule-discriminating molecule, has been used as an enzyme model, since it exhibits an enzyme-like behavior such as stereoselective acceleration leading to a stereoselective product,... 

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