Tnfluoromethylcopper

A similar distribution of copper reagents can be obtained via the direct reaction of copper metal with dibromodifluoromethane or bromochlorodifluoromethane in DMF at 85-95 °C [212] The oligomerization can be supressed via the addition of alkali metal fluorides to the reaction mixture [2/2] When HMPA is added to the tnfluoromethylcopper solution, decomposition is slowed, and this solution can be used to trifluoromethylate aromatic iodides [210] (equation 143). 

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