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Thyroid hormone-binding ratio

Free Hormone Fraction by Uptake Methods Thyroid Hormone-Binding Ratio)... [Pg.2076]

Thyroid Hormones. Iodine, absorbed as P, is oxidized in the thyroid and bound to a thyroglobulin. The resultant glycoprotein, mol wt 670,000, contains 120 tyrosine residues of which ca two-thirds are available for binding iodine in several ways. Proteolysis introduces the active hormones 3,5,3 -triiodothyronine (T ) and 3,5,3, 5 -tetraiodothyronine (T, (thyroxine) in the ratio Ty.T of 4 1 (121,122). [Pg.386]

Table 1. Tissue responsiveness to thyroid hormone. Effect of thyroid hormone on oxygen consumption and malic enzyme mRNA levels compared to nuclear T3-binding capacity. Data for selected tissues in adult rats were adapted from the cited references. Oxygen consumption (cu.mm./mg wet weight/h) is the ratio in euthyroid versus thyroidectomized (Tx) rats. The fold of induction of malic enzyme mRNAs was calculated from values obtained from tissues of euthyroid rats and rats treated for 10 days with ISpg T3/IOO g b.w. The binding capacity was measured in normal rats. Table 1. Tissue responsiveness to thyroid hormone. Effect of thyroid hormone on oxygen consumption and malic enzyme mRNA levels compared to nuclear T3-binding capacity. Data for selected tissues in adult rats were adapted from the cited references. Oxygen consumption (cu.mm./mg wet weight/h) is the ratio in euthyroid versus thyroidectomized (Tx) rats. The fold of induction of malic enzyme mRNAs was calculated from values obtained from tissues of euthyroid rats and rats treated for 10 days with ISpg T3/IOO g b.w. The binding capacity was measured in normal rats.
See other pages where Thyroid hormone-binding ratio is mentioned: [Pg.2513]    [Pg.2054]    [Pg.2513]    [Pg.2054]    [Pg.454]    [Pg.458]    [Pg.409]    [Pg.503]    [Pg.259]    [Pg.325]    [Pg.894]    [Pg.203]   
See also in sourсe #XX -- [ Pg.2076 , Pg.2077 ]



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