Thiolysis, Alkanethiolysis, Arenethiolysis, or Arenesulfinolysis of Extranuclear Halogenoquinoxalines

Thiolysis, Alkanethiolysis, Arenethiolysis, or Arenesulfinolysis of Extranuclear Halogenoquinoxalines 

Of these processes, thiolysis appears to have been unused in recent years perhaps because the resulting mercaptoalkyl products are very prone to aerial oxidation. The following examples illustrate procedures that afford sulfides or sulfones. 

3-Bis(bromomethyl)quinoxaline and 4-amino-l,3,4-triazole-3(2//)-thione gave 2,3-bis(4-amino-l,2,4-triazol-3-ylthiomethyl)quinoxaline (281) (KOH, EtOH, 20 C reflux, 1 h 71% analogs likewise).1 

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