Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Thiazolium salts, deuterium exchange

The next coenzyme for which a mechanism was established was thiamin pyrophosphate [3]. Ronald Breslow used nmr spectroscopy to show that the hydrogen atom at C-2 of a thiazolium salt rapidly exchanges with deuterium in even slightly alkaline solutions (6), so that the coenzyme offers an anionic centre for catalysis (Breslow, 1957). With this established, Breslow could confidently offer the pathway shown in Scheme 2 for the action of the... [Pg.9]

Desensitizers, in photography. 78 Deuterium, exchange with proton-2 of thiazolium salts, 31 Deviation theory. 69 Dialkylacyiphosphonates. adducts with thiazolium salts. 35... [Pg.148]

Deprotonations of hetarenium salts as a source of NHCs can be traced back to at least the first half of the 20th century. In 1943, thiazoHum salts were found as catalysts for benzoin condensations (1943JPS(JP)269), and in 1957, Breslow reported on the rapid deuterium exchange of thiazolium salts 42 via the anion at C-2 of thiazolium salts (i.e., the NHC 43 which also plays a role in vitamin Bl) (Scheme 11), and correspondingly, of 1,3-dimethylbenzimidazoHum iodide (1958JA3719). These results also inspired... [Pg.150]

See other pages where Thiazolium salts, deuterium exchange is mentioned: [Pg.2]    [Pg.114]    [Pg.390]    [Pg.410]    [Pg.3]    [Pg.528]    [Pg.65]    [Pg.185]    [Pg.410]    [Pg.413]    [Pg.772]    [Pg.24]    [Pg.70]    [Pg.11]    [Pg.70]    [Pg.70]    [Pg.167]   
See also in sourсe #XX -- [ Pg.114 ]

See also in sourсe #XX -- [ Pg.114 ]



SEARCH



Deuterium exchange

Deuterium, exchanged

Thiazolium

Thiazolium salts

Thiazoliums

© 2024 chempedia.info