The risk of a false positive finding

When zero is within the 95 per cent Cl, the results are described as nonsignificant . The use of insignificant as the opposite of significant looks uneducated. 

If the evidence is significant , it is strong enough to merit being added to whatever body of knowledge already exists. It does not mean that we should blindly accept the current result. 

1 What would happen if there was no real effect  

A major requirement of any statistical test is that it should provide protection against concluding that there is a real effect in circumstances where none really exists. This protection is considered below. 

Misleading sample. Appears to provide evidence of a difference in clearance 

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Skin testing of patients who experienced a suspected immediate allergic reactiou to an NMBD should be undertaken no earher than 4-6 weeks after the reaction. Since most of the IgE antibodies may have been consumed during the allergic event, testing within the 4-6 week period increases the risk of a false-positive finding, so only positive results should be taken notice of and a negative test should be repeated after the... 

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